NICOTINAMID ADENINE DINUCLEOTIDE
WHAT IS NAD+?
- NAD + or Nicotinamide adenine dinucleotide is a vitamin B3 derivative. A natural compound that plays an important role in determining the life expectancy of cells in the body.
- NAD + also has been identified as the key to cellular metabolism. As a source of energy in metabolic processes of more than 5,000 cell types and stimulate the cellular proliferation mechanism
- NAD + is a key coenzyme in cellular regeneration at the DNA level.
- NAD + activates Sirtuins enzymes that open genes in the body which increase energy metabolism, reduce inflammation, prevent dementia, and prolong health
NAD+ Level
NAD+ is one of the most important molecules in the body. The level of NAD+ in our body decreases naturally, more than 50% as we get older. With middle age, it will reduce to less than 50% and will be reduced continuously to 1%–10% into old age.
A decrease in NAD+levels results in the deactivation of the Sirtuins protein and inhibition of thePARP1 enzyme, both of which result in deterioration of the nervous system, memory, reduced energy conversion levels, and the aging of cells.
NAD and PARP1
NAD helps improve PARP1's performance. PARP1 is an enzyme that enhance to the process of stimulating the repair of damaged DNA from free radicals, UV rays, or chemicals.
NAD and SIRT activity (Silent Information Regulator) is a protein that is important to the process of dying of inflammatory cells and the resistance to stress of cells, ask well as promoting longevity of life. Furthermore, it helps cells and the body use energy more efficiently.